It’s a universal fact that fleas and ticks can infest our furry friends at any given time from anywhere and spread fatal diseases, if left untreated. Well, pet parents may be well aware of the immense threat caused by parasites and realize that it requires to be eliminated immediately. Here we’ve made the task easier for you to choose the right product for your pet by comparing two of the popular products in the market – Comfortis and Comfortis Plus. Comfortis and Comfortis Plus have earned a great reputation and have secured its place in the pet parents ‘add to cart’. Belonging from the same manufacturer and being the same brand, the two products still function a bit different on your pet. So, let’s take a look at both the products and consider the one which you feel is the best for your dog.


Subject Comfortis Comfortis Plus
Introduction Comfortis is a highly potent and very effective flea treatment for dogs. It comes in beef-flavored tablets, which help in eliminating fleas and preventing flea infestations. Comfortis Plus treats fleas and flea infestation in dogs and puppies. The chew also treats worms as well as controls heartworms.
Active Ingredients Spinosad Spinosad, Milbemycin Oxime
How Does It Work
  • Comfortis consists of an active ingredient called Spinosad.


  • This environment-friendly ingredient eradicates fleas by causing excitation of the insect’s nervous system, which eventually lead to their paralysis and quick death.
  • Comfortis Plus contains two active ingredients Spinosad: Spinosad attacks the neurons, which cause involuntary muscle contractions and eventually lead to paralysis. Hence, all the fleas are destroyed.
  • Milbemycin Oxime: oxime works on intestinal worms and immature heartworms. Thus, it eliminates these parasites and protects dogs against harmful heartworm and common worm infections.
Fleas The beef-flavored treatment starts eliminating fleas within 30 minutes of administration. It kills fleas before they lay eggs. Eliminates fleas within 4 hours of administration. Comfortis Plus starts killing fleas within 30 minutes and destroys 100% fleas within 4 hours of administration.
Intestinal Worms


The oral treatment provides protection to the dog against intestinal worms.
Heartworms The monthly treatment prevents heartworm disease in dogs.
Other Parasites Controls Flea Allergy Dermatitis Controls Flea Allergy Dermatitis
Efficacy Monthly treatment  

Monthly treatment


Safe To Use Safe for dogs and puppies 14 weeks and older. Consult a veterinarian before treating breeding, lactating, pregnant or epileptic dogs.  

The monthly treatment can be used in puppies from 8 weeks of age. Do not treat pregnant or lactating dogs.


Both of these products are equally good and effective. Comfortis is a good product to get all-around protection from fleas for your dog. Comfortis Plus is a perfect fit to eliminate fleas as well as intestinal worms from your pet and to protect them from heartworms.